hubrecht.eu. Read the new partnership agreement between Pontiac School District and the state including exhibits of data on the schools achievement gaps. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park. Oncode Investigator at Hubrecht Institute My Research Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. Other Annotations. Jop Kind Group. Jop Kind leads a Developmental Epigenomics group at Hubrecht Institute, Netherlands. Past events. Hubrecht Institute, Developmental Biology and Stem Cell Research | 6,134 followers on LinkedIn. About. 3,331. 2 day event 19 - 20 Apr. Jop Kind, Junior Group Leader at the Hubrecht Institute. A large proportion of the metazoan genome is spatially segregated at the nuclear periphery through genomic contacts with the nuclear lamina, a thin meshwork of lamin filaments that lines the inner-nuclear membrane. Jop Kind lab. Erasmus University Medical Center/ UFO Biosciences, NL . In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. Miao-Ping Chien. See what employees say about what it's like to work at Hubrecht Institute. To be announced. Here For You During COVID-19 NEW! Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. j.kind@hubrecht.eu. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. Oncode, starting from a deeper understanding of the basics of cancer, works to come up with better treatments and improved diagnostics. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to … Jop Kind, group leader at the Hubrecht Institute, has been awarded a NWO Vidi-grant. Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on the imaginative questions that led him to the prize . Jop Kind lab. KIT, Royal Tropical Institute. Salaries, reviews, and more - all posted by employees working at Hubrecht Institute. Annual Scientific Meeting. Jop Kind; Jurgen Marteijn; Titia Sixma; Organising Committee Oncode . Publications. Electronic address: j.kind@hubrecht.eu. ); s.kefalopoulou@hubrecht.eu (S.K.) Mechanisms underlying cell-fate choice in early embryogenesis A major interest in the group is how gene-expression control is achieved in early embryogenesis. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research. 13:05. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). Online event. Annual Scientific Meeting. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. In this conversation. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Job Corps is the largest Free residential education and job training program for young adults ages 16–24.. We connect you with the skills and education you need to get the career you want! j.kind@hubrecht.eu. Cited by. Online event. Kind’s work has paved the way for the development of powerful technologies to map chromatin, or balled-up DNA, in single cells, earning him this year’s John Kendrew Award. The researchers are each given two million euros to strengthen their research groups and continue their innovative research in the next 5 years. The researchers are each given two million euros to strengthen their research groups and continue their innovative research in the next 5 years. Jop Kind Group Jop Kind Oncode Investigator at Hubrecht Institute My Research. Oncode unites science, collaboration and valorization to create impact for patients. 12:35. Reads . Save the date! Furthermore, as we consider technology development a core business of the group, we are continuously exploring ways to obtain richer single-cell datasets. ). 3584 CT Utrecht Network. Jop Kind. As a postdoctoral fellow in the lab of Bas van Steensel at the NKI, Jop developed novel techniques to visualize and profile single-cell spatial genome organization. Ester Frische; Mariëlle Harlé; Yuva Oz; Jacqueline Staring; Peter Thijssen; More information will follow. Seeing is sequencing: linking phenotypes and genotypes of heterogeneous cancer cells by high-throughput, microscopy-based single cell selection and functionally annotated single cell sequencing. Duplicate citations. Jop Kind Group Leader at Hubrecht Institute, Developmental Biology and Stem Cell Research Amsterdam en omgeving, Nederland Meer dan 500 connecties PMID: 32350457 DOI: 10.1038/s41596-020-0314-8 Since October 2014 he is Junior Group Leader at the Hubrecht Institute. Jop Kind is group leader at the Hubrecht Institute and Oncode Investigator. Visit Kind's page. By Jop Kind, Hubrecht Institute. Self-organization in embryology. Their combined citations are counted only for the first article. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, Molecular mechanisms and regulation of DNA repair; Hubrecht Institute. Additionally, they study how new cell types arise in the early development of mouse embryos, in which epigenetics plays an important role. Wouter de Laat Group. The following articles are merged in Scholar. Kim L de Luca 1 , Jop Kind 2 ... 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. ). Additionally, they will investigate whether there are other, currently unknown pathways involved in repairing ICLs. Tumor-cell trajectories in organoid and mouse models Verified email at hubrecht.eu. He will zoom in on single-cell epigenomics and multi-omics. Friends raise €290.800,- for Hubrecht Institute. Over 17 years of experience in Molecular Biology, Yuva completed her MSc. Biography. Read more | 18 November . The aim of the lab is to understand the principles governing cellular decision-making. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Institute of Molecular Biotechnology, Austrian academy of science. Jop Kind is group leader at the Hubrecht Institute and Oncode investigator. 3 day event 20 - 22 Jan. Masterclass: Artificial intelligence and deep learning in basic research and clinical practice in Oncology: In-depth sessions. That way, we hope to better understand the relationship between epigenetics and the emergence of new cell types”, says Kind. Go to Website Navigation: Home; about narcis; login; Nederlands; contact. Puck Knipscheer Group. Geert Kops Group. Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Genome instability; UMC Utrecht. To obtain detailed insight into this trajectory, it is essential to capture all the stages with single-cell accuracy. Nicolas Rivron. 23. Over 17 years of experience in Molecular Biology, Yuva completed her MSc. Oncode is an independent institute dedicated to understanding cancer and translating research into practice. We are interested in how cells acquire new identities and traits in lineage specification events in mice and in cancer. We are employing scDam&T to obtain a better understanding of the epigenetic mechanisms underlying lineage decisions in early embryogenesis, to identify the epigenetic trajectories of single cells that acquire malignant identities in tumorigenesis and to obtain insight into the role of chromatin in DNA double-strand repair. The Kind group researches gene regulation – how genes are turned on or off – and the influence of the packing of DNA, the epigenetics, on this mechanism. Save the date for our Annual Conference! jop kind Hubrecht Institute Verified email at hubrecht.eu. Jop Kind The organization of DNA within the eukaryotic nucleus is important for cellular processes such as regulation of gene expression and repair of DNA damage. ERC-starting grant for Marvin Tanenbaum and Jop Kind Marvin Tanenbaum and Jop Kind, both group leader at the Hubrecht Institute, are awarded an ERC-starting grant. The grant enables them to develop their own innovative line of research and set up their own research group. To achieve this, we make use of organoid and mouse models that capture tumorigenesis all the way from the initiating stages towards metastasis. To be announced. Accurate repair of DNA damage is critical for the maintenance of genomic integrity. Hubrecht Institute opens new laboratory building. This method enables linking transcriptional variability to epigenetic heterogeneity. To study DSB-repair in single cells, we have adapted scDam&T to generate maps of DSB-repair sites in single cells. Because DamID-signals are stable and can be carried-over for multiple generations, we are also looking into ways to exploit this property of DamID to study DSB-repair in the context of cellular decision making. Dive into the research topics where Jop Kind is active. About the Hubrecht Institute torres-padilla@helmholtz-muenchen.de. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Susanne Lens Group. This "Cited by" count includes citations to the following articles in Scholar. The John Kendrew Young Scientist Award (JKA) was launched in 2007 as an initiative from the EMBL Pensioner’s Association to honour EMBL’s first Director General, Sir John Kendrew (1975-1982), and to support scientists in the early stages of their career. Publications 23. Cell-fate decisions and the role of epigenetics in DNA double-strand repair She and others previously discovered that the Fanconi anemia (FA) pathway plays a crucial role in repairing ICLs. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Jop Kind EMBL: Predoc, Akhtar group, Genome Biology, 2002-2008. Because DamID-signals are stable and can be carried-over for multiple generations, we are also looking into ways to exploit this property of DamID to study DSB-repair in the context of cellular decision making. Bob Roberts 2020-06-07 16:21:36 ? Projects 1. Afterwards, Alexander van Oudenaarden, Mauro Muraro and Waleed Kholosy will also give talks and elaborate on some specific applications and usage of single cell technology. Kim L de Luca 1 , Jop Kind 2 Affiliations 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. Year; Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Award ceremony photo gallery. j.kind@hubrecht.eu. Save the date for our Annual Conference! Despite extensive research into the molecular pathways that sense and repair DNA double-strand breaks (DSBs), comparatively little is known about management of breaks within different genomic and chromatin contexts. Further, in the same cells, we also profile genome-wide chromatin states with a chromatin immunocleavage (ChIC) approach to study the relationships between DSB-repair and the local chromatin environment (Figure 3). The researchers in Kind’s group will use the ERC grant to further research when and how cells make these identity choices. Wouter de Laat Group. Network. PMID: 31118510 PMCID: PMC6546605 The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Silke J. Contact Information Mariëlle Harlé Other Events. j.kind@hubrecht.eu. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. In total the NWO has awarded 87 experienced researchers a Vidi grant worth 800,000 euros. Spatiotemporal regulation of genomic function; Hubrecht Institute. Puck Knipscheer is group leader at the Hubrecht Institute and Oncode investigator. Jop Kind obtained his PhD from the Radboud University in Nijmegen for his work on dosage compensation in the lab of Asifa Akhtar at the EMBL Heidelberg. Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ Merged citations. Verified account Protected Tweets @; Suggested users Furthermore, they aim to develop new techniques with which they can simultaneously perform multiple measurements in a single cell. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). Jop is currently an associate professor at the Hubrecht Institute in Utrecht where his lab continues to develop new techniques to single-cell profile gene-regulation to obtain better insights into the mechanisms that govern cell fate choice in development and disease. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, The Netherlands; s.lochs@hubrecht.eu (S.J.A.L. Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ PhD. He made visible how 6 feet of DNA is dispersed in a cell nucleus of 10 micrometres. His group is focused on understanding how spatial and temporal changes in genome architecture affect gene expression. Contact. 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